Novartis Pharmaceuticals Job Description Summary We are seeking an innovative and dynamic Principal Scientist II with extensive expertise in neuroscience and animal behavior to join our Emerging Technologies team in Comparative Medicine. This team focuses on exploring in vivo digital biomarkers using state-of-the-art, non-invasive technologies such as digital home-cage monitoring solutions. In this role, you will drive research programs aimed at discovering novel digital measurements and biomarkers through technologies like video monitoring. Your work will provide researchers with deeper insights into animal behavior and disease onset, enhancing model definition and decision-making processes in research. Additionally, you will contribute to the welfare of the animals and the application of the 3Rs principles (Reduction, Refinement, Replacement). Job Description Major Accountabilities: Contribute to the Biomedical Research drug discovery process by advancing the...

Site Name: USA - Pennsylvania - Upper Providence Posted Date: Sep 5 2024 Are you a scientist in sterile product formulation and injectables eager to lead the development of life-changing drug products? Are you eager to unite science, talent, and technology to get ahead of disease together? This may be the right opportunity for you! This role is Hybrid at our Upper Providence, PA site and does require minimum 2-3 days on-site per week. As a Biopharmaceutical Drug Product, Principal Scientist/ Investigator, you will join the GSK sterile Drug Product Development organization and work on developing late phase drug product formulation, manufacturing process and delivery systems for protein-based therapeutics and NCEs. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Member of a team responsible for enabling the progression of new assets from candidate selection to product...

GlaxoSmithKline Are you a scientist in sterile product formulation and injectables eager to lead the development of life-changing drug products? Are you eager to unite science, talent, and technology to get ahead of disease together? This may be the right opportunity for you! This role is Hybrid at our Upper Providence, PA site and does require minimum 2-3 days on-site per week. As a Biopharmaceutical Drug Product, Principal Scientist/ Investigator, you will join the GSK sterile Drug Product Development organization and work on developing late phase drug product formulation, manufacturing process and delivery systems for protein-based therapeutics and NCEs. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Member of a team responsible for enabling the progression of new assets from candidate selection to product commercialization. Design, plan and execute studies for...

Site Name: USA - Pennsylvania - Upper Providence Posted Date: Sep 4 2024 Are you looking to enhance your bioanalytical expertise by working for a global pharmaceutical company that allows you to leverage best in class LC-MS systems and technologies? If so, this Principal Scientist role is the ideal opportunity for you. At our world-class scientific hub in Upper Providence, Pennsylvania, our Biomarker and Bioanalytical Platforms (BBP) department currently has an exciting career opportunity for a talented individual with a passion for the analytical sciences and applying their skill set to addressing human disease. As a Principal Scientist within the LC-MS Bioanalysis group, you will be responsible for the development and validation of assays to deliver PK and PD endpoints for clinical studies across the GSK portfolio. Data from this group is a key component to understanding molecules in the GSK pipeline and serves to make early and informed decisions for asset progression...

PerkinElmer Responsibilities Location Collegeville, PennsylvaniaUS Job ID REQ-053451 Job Responsibilities: Conduct laboratory experimentation and analytical testing of putative formulations & drug product manufacturing Follow administration/delivery approaches for select protein therapeutic assets, including contributing to, the conception & evaluation of conventional & novel product matrices and administration modalities Partner closely with the manufacturing groups during process development and technology transfers Actively participate with combination drug product assessment and collaborate with device engineering Physicochemical and bioanalytical characterization of native and modified biopharma compounds Collaborate with the Bioanalytical Sciences group to develop & transfer stability-indicating analytical methods for use in product development Oversee release & stability testing; crafting & execution of non-GMP stability protocols...

AstraZeneca Associate Principal Scientist Immunology AstraZeneca is a global, science-driven biopharmaceutical company. We are dedicated to discovering, developing, and delivering innovative, meaningful medicines and healthcare solutions that enrich the lives of patients. The vision of AstraZeneca Early Respiratory & Immunology (Early R&I) is centered on delivering life-changing products that advance world health and help fight and cure disease. Early R&I is one of three main therapeutic research areas within AstraZeneca that deliver candidate drugs into late-stage clinical development. Here, you'll have the opportunity to make a difference in people's lives every day. As a part of the growing Immunology Bioscience team within Early R&I department, we are seeking a highly motivated senior researcher with a strong understanding of adaptive and innate immunity and the key biological pathways underlying immune-mediated diseases in rheumatology and preferably...

Novartis Pharmaceuticals Job Description Summary Principal Scientist I/II, Radioligand Modeling & Simulation This position will be located in Cambridge, MA and will not have the ability to be located remotely. #LI-Hybrid About the role: We are seeking a translational or clinical modeler eager to accelerate radioligand discovery & development by facilitating rigorous decision making with modeling & simulation. You will work in a multi-disciplinary environment, with opportunities to engage in cross-functional initiatives. This role reports to a PK Sciences Translational Modeling team lead, in a group situated within Biomedical Research, the research engine of Novartis. Job Description Key responsibilities: Act as the Translational M&S representative on radioligand therapy programs, developing and executing modeling strategies, contributing to project team discussions, and guiding therapeutic design and dose selection decisions. Build...

The Azek Company The Principal Engineer, Building Systems and Components Design, reporting to the Director, R&D, is expected to be a recognized expert and a key and critical contributor providing novel designs that create value through ease of installation and materials optimization. These designs will initial focus on our railing systems (composite, aluminum, and steel), but will expand over time as the team grows to include work on decking, cladding, and exterior wall assemblies and components. You will lead the design and structural analysis of the systems and components along with their transitions to internal and external manufacturing partners. You will coordinate with the Materials and Structural Testing Group on testing to achieve the required code performance. Coordinate/fabricate 3-D models and other prototypes to demonstrate features and installation methods to the project team. The individual is a company expert for design, modeling, and analysis of these...

Alkermes, Inc. Position Summary: The Principal Scientist position within Analytical Development provides technical leadership for small molecule analytical methodologies and grows as a subject matter expert both within and outside the department as part of a growing, dynamic Pharmaceutical Development organization. They will work within the Analytical Development team to characterize drug substance, drug product, impurities, degradants, and metabolites from pre-clinical research through drug development and commercialization. The successful candidate will thrive in a highly collaborative matrix team environment to drive critical decision-making and ensure the successful development of new drugs. PDN-9bbb39b9-00a9-418a-b5fb-5c994d8f0f52

Novartis Pharmaceuticals Job Description Summary #LI-Hybrid About the role: The position is located in Cambridge, MA and will not have the ability to be located remotely. This role reports to a PK Sciences (PKS) Dax (renal and liver diseases) and DARe (diseases of aging and regenerative medicine) therapeutic areas within Translational Medicine (TM) in Biomedical Research. PKS is a global organization of about 300+ associates, situated within Translational Medicine (TM), the clinical research arm of Biomedical Research within Novartis. PK Sciences plays a pivotal role in bringing innovative medicines to patients, by building on research advances to develop new therapies, bridging drug discovery and clinical application. PK Science is an enterprise-wide organization, working across both Biomedical Research and the Development organizations to advance the scientific knowledge of pharmacokinetics, metabolism and clinical pharmacology. We are seeking an enthusiastic and...

Novartis Pharmaceuticals Job Description Summary Location: This position will be located in Cambridge, MA and will not have the ability to be located remotely. #LI-Hybrid About the role: We are seeking an experienced translational or clinical modeler eager to accelerate radioligand discovery & development by enabling rigorous decision making with modeling & simulation. You will work in a multi-disciplinary environment, with opportunities to engage in and/or lead cross-functional initiatives. This role reports to a PK Sciences Translational Modeling team lead, in a group situated within Biomedical Research, the research engine of Novartis. Job Description Key responsibilities: Act as the Translational M&S representative on radioligand therapy programs, developing and executing modeling strategies, contributing to project team discussions, and guiding therapeutic design and dose selection decisions. Build and apply innovative QSP and...

Site Name: USA - Pennsylvania - Upper Providence Posted Date: Sep 4 2024 Are you energized by the challenge of designing innovative ways to use Engineering, Process Analytics Technologies, Automation and Modelling to develop medicines for patients? If so, this opportunity within the Sterile Process Engineering team would be the right fit for you. Our team in the Process Engineering group is passionate about the work we do, and we’d be eager to welcome individuals with a similar interest in using technology to develop medicines. As an Investigator, you will employ knowledge and experience of drug product unit operations, Process Engineering, and modelling to assess, develop and implement new manufacturing platforms and support scale-up, technology transfer and manufacture of Biopharmaceutical drug product through to commercialization. You will work very closely with automation experts and data scientists to enable efficiencies during drug product development. This...

Capital One Center 2 (19050), United States of America, McLean, Virginia Principal Data Scientist, Consumer Identity Machine Learning Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and the relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data-driven decision-making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description Consumer Identity ML is the data science and machine...

Capital One Center 2 (19050), United States of America, McLean, Virginia Principal Data Scientist, Consumer Identity Machine Learning Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and the relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data-driven decision-making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description Consumer Identity ML is the data science and machine...

Capital One Center 2 (19050), United States of America, McLean, Virginia Principal Data Scientist, Consumer Identity Machine Learning Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and the relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data-driven decision-making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description Consumer Identity ML is the data science and machine...

Capital One Center 2 (19050), United States of America, McLean, Virginia Principal Data Scientist, Consumer Identity Machine Learning Data is at the center of everything we do. As a startup, we disrupted the credit card industry by individually personalizing every credit card offer using statistical modeling and the relational database, cutting edge technology in 1988! Fast-forward a few years, and this little innovation and our passion for data has skyrocketed us to a Fortune 200 company and a leader in the world of data-driven decision-making. As a Data Scientist at Capital One, you'll be part of a team that's leading the next wave of disruption at a whole new scale, using the latest in computing and machine learning technologies and operating across billions of customer records to unlock the big opportunities that help everyday people save money, time and agony in their financial lives. Team Description Consumer Identity ML is the data science and machine...

Biogen Company Description HI-Bio, Inc. is a Biogen company based in South San Francisco, California. As of July 2, 2024, we are part of Biogen's global team, with a commitment to excellence and a pioneering spirit. As part of a mid-sized biotechnology company, we offer the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission: Caring Deeply, Achieving Excellence, Changing Lives. Our team in San Francisco is specifically focused on transforming the lives of patients with severe immune-mediated diseases by developing novel targeted therapies with outsized clinical impact, faster. To accomplish this, we are seeking top...

Biogen Company Description HI-Bio, Inc. is a Biogen company based in South San Francisco, California. As of July 2, 2024, we are part of Biogen's global team, with a commitment to excellence and a pioneering spirit. As part of a mid-sized biotechnology company, we offer the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission: Caring Deeply, Achieving Excellence, Changing Lives. Our team in San Francisco is specifically focused on transforming the lives of patients with severe immune-mediated diseases by developing novel targeted therapies with outsized clinical impact, faster. To accomplish this, we are seeking top...

Biogen Company Description HI-Bio, Inc. is a Biogen company based in South San Francisco, California. As of July 2, 2024, we are part of Biogen's global team, with a commitment to excellence and a pioneering spirit. As part of a mid-sized biotechnology company, we offer the stability and resources of a well-established business while fostering an environment where individual contributions make a significant impact. Our team encompasses some of the most talented and passionate achievers who have unparalleled opportunities for learning, growth, and expanding their skills. Above all, we work together to deliver life-changing medicines, with every role playing a vital part in our mission: Caring Deeply, Achieving Excellence, Changing Lives. Our team in San Francisco is specifically focused on transforming the lives of patients with severe immune-mediated diseases by developing novel targeted therapies with outsized clinical impact, faster. To accomplish this, we are seeking top...

AstraZeneca Job Title: Director Principal Patient Safety Scientist Location: Gaithersburg MD (3 days on site) At AstraZeneca , we deliver life-changing medicines to millions of people globally. Our purpose is ambitious and so is our approach. Crafting a more agile and inclusive environment means building an inspiring culture where we celebrate innovative thinking. Our strategy and ability to transform our medicines portfolio means we have a drug-development pipeline that presents incredible opportunities to push the boundaries of science. Faced with complex disease challenges, we focus on outstanding performance to drive the world's best and most progressive drug development programs. Our team is looking for a Director, Principal Patient Safety (PS) Scientist to lead the strategy for proactive PV and risk management planning of multiple complex products within the Oncology Therapeutic Area. In this exciting and challenging role, you will work collaboratively with...