11 application engineering manager jobs found in Waltham

Repligen Overview Make a global impact-join Repligen. We're united by a mission to inspire advances in bioprocessing as a preferred partner in the production of biologic drugs that improve human health worldwide. No matter your role or background, at Repligen, you will play a key part in shaping some of the most innovative and life-changing therapies in the world. We foster a culture of purpose, collaboration, and shared success-where every voice matters and every contribution drives progress. Join us! Why you should consider us? Repligen has fast become one of the technology innovators and leaders in the world of bioprocess. With the addition of C Technologies and it's market leading VPT (Variable Pathlength Technology), Repligen is now at the forefront of PAT (Process Analytics Technology) with a growing portfolio of at-line and in-line solutions. As part of Repligen, your work will help accelerate the drug development process, ensure the reproducibility of its...

Wabtec Company Description Evident's Inspection Technologies division is now a part of Wabtec Corporation. Read more. Job Description The incumbent will design mechanical systems as part of the development of new products related to the test and measurement market in an agile R&D setting. The incumbent will supervise and approve the work of designers under their supervision where applicable and ensure an exemplary level of quality in the concepts developed. The incumbent will work in collaboration with multidisciplinary teams in a state-of-the-art development environment.   Specific Responsibilities General Product Development: Contribute to the analysis, understanding and documentation of product requirements and functionalities in collaboration with the  project lead and other disciplines; Develop and propose mechanical concepts as part of product development; Develop the mechanical performance requirements of the parts and assembly (norms and standards,...

Alkermes, Inc. Alkermes is seeking an experienced Program Manager to support our ALKS 2680 program which is currently in Phase 2 development and preparing for Phase 3 and registration. ALKS 2680 is a novel, investigational, oral, selective orexin 2 receptor (OX2R) agonist in development as a once-daily treatment for narcolepsy and idiopathic hypersomnia. This person will work closely with members across our organization including areas such as research, pre-clinical, clinical, pharmaceutical development, regulatory affairs, medical affairs, commercial, operations, policy and government affairs, patient engagement and corporate communications, as well as the senior management team to orchestrate development and execution of our fully-integrated program strategic and operational plans to support key corporate goals including the development and ultimate approval of ALKS 2680 as well as identify and execute a comprehensive lifecycle management program. This is a hybrid on-site...

Alkermes, Inc. We're looking for a strategic, technically sharp leader to take ownership of Alkermes' cloud and Linux platform ecosystem. This role sits at the center of our enterprise and R&D technology landscape and is responsible for the performance, reliability, and compliance of our AWS workloads and Linux compute environments across both cloud and onprem systems. You'll bring deep platform engineering experience plus the ability to steer a modern managedservices model. You'll shape how our cloud and Linux platforms evolve - partnering closely with Enterprise Architecture, Cloud Architects, and IT Functional Leads - ensuring our environments remain scalable, secure, compliant, and ready for the scientific and business demands ahead. In this role, you'll set the technical direction, guide engineering approaches, and ensure our platforms run with strong operational discipline. Your work will directly support scientific computing, enterprise workloads, and the broader...

National Grid Hourly Pay Rate - $44.59 Location - Waltham Job Purpose The Permitting Aide develops drawings as necessary to support the acquisition of certain road opening permits for gas construction projects. Need for permit may be identified by engineering, sales, legal, project sponsors, construction support functions or other entities as needed. Performs work under supervision of management employee(s) responsible for managing and prioritizing the work required to generate permit requests. Key Accountabilities Generate drawings to obtain road opening permits for gas construction where Computer Aided Design (CAD) software is necessary for the level of detail required by permit agency. Permits include MASSDOT, Department of Conservation and Recreation (DCR), and various city/town Grant of Location requests. Tasks associated with 'generate drawings include: Obtain and/or assemble data required for creation of drawings. Data may include street lines, property...

Alkermes, Inc. The Summer Intern will support the Genomic Sciences and Target Discovery team in strengthening the rigor, efficiency, and scalability of early target assessments through the application of AI/ML methods. This role will focus on building computational frameworks, data and AI-driven workflows that enable real-time competitive intelligence, improved target dossier generation, and systematic target prioritization. The intern will gain hands-on experience at the interface of data science, machine learning, and early discovery research, with opportunities to contribute directly to platform development that informs neuroscience and psychiatric drug discovery. Qualifications Basic Qualifications: Current enrollment in a Master's or Doctoral program in one of the following fields: Computer Science Data Science or Machine Learning Computational Biology Bioinformatics Computational Neuroscience Or a related quantitative discipline Preferred...

Alkermes, Inc. The Senior Director, Emerging Technology and Engineering is a critical leadership role responsible for defining the company's technology future across Enterprise Architecture, Data, Advanced Analytics, and core Engineering practices. This role manages an integrated function to ensure our IT roadmap, digital strategy, core technologies, and AI/Analytics capabilities are designed to drive competitive advantage, accelerate business insights, enhance decision-making, and are implemented with high-quality engineering standards. The Senior Director will serve as a primary interface for the Emerging Technology and Engineering Team within the Global IT organization while championing the adoption and maturity of advanced data and analytical capabilities across the enterprise. This role will work a hybrid weekly office schedule in our Waltham location. Responsibilities Strategic Leadership Build and mature IT capabilities to support current and emerging...

Alkermes, Inc. Associate Director, External Operations API API process expert responsible as the technical lead representative supporting API manufacturing at Contract Manufacturing Organizations' (CMO's) and subsequent processing of API's in Drug Product (DP) processes across OSD and injectables. Required to support new product introductions, technology transfers, continually monitor and improve API operations conducted at CMO's on behalf of Alkermes. Responsibilities General Review and maintain Alkermes practices & systems in managing contract manufacturers to ensure compliance with cGMP, and other regulatory requirements - ensuring that appropriate policies, rules, regulations and agreements are followed. Understanding of chemical processes from both scientific and engineering perspective demonstrating expertise in how API processes are developed and controlled to maximize yield and minimize impurities. Perform trending on CMO API processes and identify...

Alkermes, Inc. Position Summary: The Process Development Technician supports the execution of experimental studies to develop well-understood, robust oral solid dosage (OSD) manufacturing processes. Key responsibilities include equipment setup, cleaning, troubleshooting, execution of experiments, and data collection to identify and implement process and equipment improvements that reduce waste and increase process reliability. This role plays a key part in maintaining GMP standards within the pilot facility and supporting the manufacture of clinical supplies. Responsibilities: Support the set up and operation of a new GMP clinical manufacturing suite with a broad range of processing capability and technology approaches.Operate, maintain, and troubleshoot a variety of process equipment, rapidly assimilating and applying new technologies as introduced.Perform equipment and room cleaning in compliance with established housekeeping and GMP standards.Assist in...

Alkermes, Inc. Job Title Senior System Analyst III - Clinical Manufacturing Suite Location Waltham, MA (Hybrid Office Schedule) Position Summary The IT Senior System Analyst III for Clinical Manufacturing Suite will lead all technology implementation, production support, and maintenance activities within the Clinical Manufacturing Suite, ensuring systems are reliable, secure, and compliant with GMP and GxP requirements. This position will be responsible for authoring and enforcing SOPs to meet GMP guidelines, onboarding and validating new equipment, maintaining compliance of existing systems, and driving the implementation of new IT GxP solutions such as Data Historian and LIMS. Partnering closely with CMC, quality, and regulatory teams, the IT Senior System Analyst III ensures alignment with FDA and global regulatory standards while fostering continuous improvement, operational excellence, and strong collaboration across the organization. The role requires deep...

Alkermes, Inc. We are seeking a highly motivated, experienced hands-on Associate Director of Information Security (Cloud and Emerging Technology) to take a leadership role in shaping and executing the organizations security strategy in advanced technologies. Reporting to the Director of Information Security, this position will oversee a small team of security professionals and act as a trusted advisor across IT, and business units. This role will be responsible for developing, implementing, and enforcing security frameworks and guardrails for cloud environments (primarily AWS), AI/ML platforms, Large Language Models (LLMs), and DevSecOps practices. In this role, the Associate Director will lead efforts to secure cloud and emerging technologies, ensuring compliance with regulatory requirements and alignment with organizational risk appetite. Responsibilities Essential Duties and Responsibilities Lead, mentor, and manage a small team of security professionals, fostering...