10 jobs found

Merck Job Description The Sterile Product Development (SPD) group is responsible for developing non-oral dosage forms (injections, implants, inhaled, ocular) for small, intermediate, and large molecules from preclinical toxicology studies to commercialization. Our development teams ensure robust composition, primary packaging/device, and process selection through deep fundamental understanding and characterization such that the process is scalable without compromising stability, safety, efficacy, and delivery. During development, we leverage smart experimental design, cutting edge analytical tools, and predictive approaches to inform molecule, formulation and process selection. In summary, our team enables the translation of preclinical candidates into non-oral drug products. Our team is looking for a strong candidate for the position of Principal Scientist (R5) within the Biologics product development group. Primary duties: Be a seasoned biologics product developer...

Merck Job Description Associate Principal Scientist, Small Molecule Analytical Research & Development The Small Molecule Analytical Research and Development (SMAR&D) group has an exciting opportunity for an Associate Principal Scientist based in Rahway, NJ. Join us and experience our culture firsthand - one of strong ethics & integrity, diversified experiences, exceptional science and a resounding passion for improving human health through innovative drug delivery technologies and predictive analytical tools. As part of our global team, you will have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. As an Associate Principal Scientist, you will be part of a team developing innovative analytical methodologies for medicines based on small molecules, peptides, mRNA, oligonucleotides and bioconjugates. Our responsibilities range from early stage up to commercialization for both drug substance and...

Merck Job Description Job Description: In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Responsibilities: The Senior Statistical Programmer, Submission Data Standards Quality Management (SDS QM), provides oversight and quality management of submission data standard deliverables for world-wide regulatory application submissions of drug and vaccine clinical development projects. Accountability predominantly includes submission data standards planning activities, coaching and consulting with project teams, outreach to external vendors and partners, and keeping current with industry...

Merck Job Description Sterile Product Development (SPD) group is responsible for developing non-oral dosage forms (injections, implants, inhaled, ocular) for biologics, mixed modalities, vaccines and small molecules from preclinical toxicology studies to commercialization. Our development teams ensure robust composition, primary packaging/ device, and process selection through deep fundamental understanding and characterization such that the process is scalable without compromising stability, safety, efficacy, and delivery. During development, we leverage smart experimental design, cutting edge analytical tools, and predictive approaches to inform molecule, formulation and process selection. In summary, our team enables the translation of preclinical candidates into non-oral drug products. Primary Responsibilities Designing and developing sterile products for biologics (monoclonal antibodies, fusion proteins, antibody-drug conjugates) drugs for injectable and...

Merck Job Description Position Description: The Environmental & Process Safety Engineering (EPSE) group within the Chemical Engineering Research & Development department (CERD), part of the Process Research and Development (PR&D) organization, is seeking highly motivated individuals who are looking for an opportunity to work in a fast-paced job that provides a high degree of technical responsibility. This position will lead and carry out independent work conceiving, designing, planning, and implementing advanced small scale laboratory studies aimed at characterizing the hazards associated with the process and materials used to produce active pharmaceutical ingredients (API) and intermediates at all scales, from the laboratory to commercial manufacturing.Specific areas include thermal hazard assessment and potential for gas generation with a variety of calorimeters such as SuperCRC, Insight, EZMax and RC1, and modeling for scale-up. This role is a leadership...

Merck Job Description Job Description: The Mixed Modalities team within Sterile Product Development is responsible for developing parenteral dosage forms (injections, implants, inhaled, ocular) for small, intermediate, and large molecules from preclinical toxicology studies to commercialization. Our development teams ensure robust composition, primary packaging/device, and process selection through deep fundamental understanding and characterization such that the process is scalable without compromising stability, safety, efficacy, and delivery. During development, we leverage smart experimental design, cutting edge analytical tools, and predictive approaches to inform molecule, formulation, and process selection. In summary, our team enables the translation of preclinical candidates into non-oral drug products. We are seeking a highly motivated candidate for the position of Associate Principal Scientist (R4) focused on developing parenteral drug products across a range...

Merck Job Description Are you ready to embark on an exhilarating career journey that combines innovation, collaboration, and impactful scientific discovery? At our company, a global leader in pharmaceuticals renowned for excellence and groundbreaking research, we are committed to improving lives through innovative medicines, vaccines, and animal health products. Protein and Structural Chemistry (PSC), a team in Discovery Chemistry (DC), supports protein structural determination from Discovery to Development, agnostic to therapeutic modalityincluding small molecule, peptide, and macromolecules. Furthermore, we elucidate the structural basis of mechanisms of action and perform analyses to support formulation development. PSC is a team of approximately 40 structural biologists who collaborate closely with medicinal and computational chemists, informaticians, mass spectrometrists, biophysicists, protein scientists, and pharmacologists to leverage state-of-the-art capabilities...

Merck Job Description The Small Molecule Analytical Research and Development group has an opening for a Senior Scientist based in Rahway, NJ. Join us and experience our culture first-hand - one of strong ethics & integrity, experiences, exceptional science and a resounding passion for improving human health through innovative drug delivery technologies and predictive analytical tools. As part of our global team, you will have the opportunity to collaborate with talented and dedicated colleagues while developing and expanding your career. In your role as Senior Scientist, you will be part of a team developing innovative analytical methodologies for early to late phase programs with application to drug substance and a broad array of drug product dosage forms, combination products and modalities through analytical characterization, imaging tools, and data analysis. You would also contribute towards regulatory submissions to enable clinical trials. Your main...

Merck Job Description In BARDS (Biostatistics and Research Decision Sciences), a distinguished department within our company's renowned Research and Development division, quantitative scientists, in partnership with other subject matter experts, apply state-of-the art scientific methodologies and tools to enable the discovery, development, regulatory approval, manufacturing, and marketing of medical drugs and vaccines for the benefit of patients and global human health. Principal Scientist, Biostatistics Are you passionate about biostatistics and eager to make a significant impact in the field of drug and vaccine development? Join our company, where we are at the forefront of research, delivering innovative health solutions that advance the prevention and treatment of diseases in people and animals. As a Principal Scientist in Biostatistics, you will play a critical role in our research & development division, contributing to the design, analysis, and...

Merck Job Description Position Description: The Environmental & Process Safety Engineering (EPSE) group within the Chemical Engineering Research & Development department (CERD), part of the Process Research and Development (PR&D) organization, is seeking highly motivated individuals who are looking for an opportunity to work in a fast-paced job that provides a high degree of technical responsibility. This position will lead and carry out independent work conceiving, designing, planning, and implementing advanced small scale laboratory studies aimed at characterizing the hazards associated with the process and materials used to produce active pharmaceutical ingredients (API) and intermediates at all scales, from the laboratory to commercial manufacturing.Specific areas include thermal hazard assessment and potential for gas generation with a variety of calorimeters such as SuperCRC, Insight, EZMax and RC1, and modeling for scale-up. This role is a leadership...