GlaxoSmithKline We are seeking motivated computational biologists to join our dynamic and expanding team. The candidates will focus on analysis and integration of diverse and complex genomic data to impact translation of our targets to the clinic. Your work will have application across our pipeline, from multi-omic characterisation of disease endophenotypes to biomarker discovery and patient stratification. The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance drug discovery and clinical development. Additionally, you will be encouraged and supported to continue to build your scientific profile through presentations, development programmes and peer-reviewed publications. Key responsibilities: This role will provide YOU the opportunity to progress YOUR career, these responsibilities include some of the following... Deliver innovative...

GlaxoSmithKline We are seeking motivated computational biologists to join our dynamic and expanding team. The candidates will focus on analysis and integration of diverse and complex genomic data to impact translation of our targets to the clinic. Your work will have application across our pipeline, from multi-omic characterisation of disease endophenotypes to biomarker discovery and patient stratification. The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance drug discovery and clinical development. Additionally, you will be encouraged and supported to continue to build your scientific profile through presentations, development programmes and peer-reviewed publications. Key responsibilities: This role will provide YOU the opportunity to progress YOUR career, these responsibilities include some of the following... Deliver innovative...

Novartis Pharmaceuticals Job Description Summary Novartis Biomedical Research is our innovation engine where public and private research merge to substantiate novel drug candidates and evaluate novel biomedical technologies to make medicine. We are seeking a creative and collaborative investigator practiced in wet and dry lab research to join our mission to develop transformative new therapies for patients with chronic renal diseases. The successful candidate will work at the cutting edge of applied data science to model and test important priorities in translational research. Your participation on project teams will require iterative mining and modeling complex, multi-modal data to drive drug discovery and early development. As a member of Novartis, the successful candidate will participate in a global community with extensive know-how and resources in data analysis, data engineering, machine learning, experimental techniques and resources to test biomedical hypotheses derived...

Site Name: Upper Providence, Cambridge 300 Technology Square Posted Date: Sep 4 2024 We are seeking motivated computational biologists to join our dynamic and expanding team. The candidates will focus on analysis and integration of diverse and complex genomic data to impact translation of our targets to the clinic. Your work will have application across our pipeline, from multi-omic characterisation of disease endophenotypes to biomarker discovery and patient stratification. The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance drug discovery and clinical development. Additionally, you will be encouraged and supported to continue to build your scientific profile through presentations, development programmes and peer-reviewed publications. Key responsibilities: This role will provide YOU the opportunity to progress YOUR career, these...

Site Name: Upper Providence, Cambridge 300 Technology Square Posted Date: Sep 4 2024 We are seeking motivated computational biologists to join our dynamic and expanding team. The candidates will focus on analysis and integration of diverse and complex genomic data to impact translation of our targets to the clinic. Your work will have application across our pipeline, from multi-omic characterisation of disease endophenotypes to biomarker discovery and patient stratification. The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance drug discovery and clinical development. Additionally, you will be encouraged and supported to continue to build your scientific profile through presentations, development programmes and peer-reviewed publications. Key responsibilities: This role will provide YOU the opportunity to progress YOUR career, these...

Children's Hospital of Philadelphia SHIFT: Day (United States of America) A Brief Overview Assume responsibility for an on-going, innovative research project as a Postdoctoral Fellow at CHOP. Our postdoc experience will broaden your skillset, scientific background, and research capabilities. CHOP Research Institute Center for Craniofacial Innovation, https://www.chopcranio.org Department of Surgery, Division of Plastic and Reconstructive Surgery has a postdoctoral position in comparative functional genomics for experienced computational biologist is available in the Cotney Lab at the Center for Craniofacial Innovation at Children's Hospital of Philadelphia Research Institute in affiliation with the Division of Plastic Surgery. Our laboratory is applying functional genomics techniques (ChIP-Seq, RNA-Seq, ChIA-PET, Hi-C, etc) to identify novel gene regulatory elements in early mammalian embryonic development. We seek to understand the genetic basis of the evolution of...

Site Name: USA - Pennsylvania - Upper Providence Posted Date: Aug 27 2024 This is an opportunity for a Chemical Biologist/Cell Biologist who has a passion for identifying and validating targets from disease-relevant phenotypic screens. You will collaborate with experts across multiple disciplines including genomic sciences, computational chemistry, biology, and medicinal chemistry. Additionally, there will be onward training in chemical biology available to you to develop your skills and progress. We require this role to be based in Upper Providence only. GSK’s Chemical Biology department supports the delivery of our early-stage pipeline of innovative medicines which is built on GSK’s strategic investment in human genetics and functional genomics. Working in partnership with GSK’s Research Units, our team of chemical biologists is accountable for the validation of novel targets identified from disease-relevant screens. Validation of these targets requires the design,...

Site Name: UK - Hertfordshire - Stevenage, USA - Massachusetts - Waltham Posted Date: Aug 22 2024 Although this role is advertised in GSK HQ and Waltham, candidates based in other locations may be considered on a case by case basis. At GSK, we have bold ambitions for patients, aiming to positively impact the health of 2.5 billion people over the next 10 years. R&D is committed to discovering and delivering transformational vaccines and medicines to prevent and change the course of disease. Science and technology are coming together in a way they never have before, and we have strong tech-enabled capabilities that allow us to build a deeper understanding of the patient, human biology and disease mechanisms, and transform medical discovery. We are revolutionising the way we do R&D. We’re uniting science, technology and talent to get ahead of disease together. Find out more: Our approach to R&D . The Department of Clinical Pharmacology Modelling and...

AstraZeneca Are you a strategically focused Regulatory professional who would like to play an integral part in bringing life changing Oncology medicines to patients? If so, please join us! At AstraZeneca, we work with diverse minds, all united by a shared passion to learn, grow and discover. Within Oncology Regulatory Science, Strategy & Excellence (ORSSE), we bring hope and solutions to patients across the globe. As Regulatory professionals working on Oncology products, we work in areas of unmet need and take innovative regulatory approaches to bring life-changing treatments to patients. Accountabilities: In this role, you will be responsible for developing, aligning, and implementing regulatory strategies to ensure successful early and late Oncology development projects on a global scale. You will serve as the global regulatory lead (GRL) on early-stage projects or specific indications of larger programs and/or as the regional regulatory lead. The successful candidate...

AstraZeneca Are you a strategically focused Regulatory professional who would like to play an integral part in bringing life changing Oncology medicines to patients? If so, please join us! At AstraZeneca, we work with diverse minds, all united by a shared passion to learn, grow and discover. Within Oncology Regulatory Science, Strategy & Excellence (ORSSE), we bring hope and solutions to patients across the globe. As Regulatory professionals working on Oncology products, we work in areas of unmet need and take innovative regulatory approaches to bring life-changing treatments to patients. Accountabilities: In this role, you will be responsible for developing, aligning, and implementing regulatory strategies to ensure successful early and late Oncology development projects on a global scale. You will serve as the global regulatory lead (GRL) on early-stage projects or specific indications of larger programs and/or as the regional regulatory lead. The successful candidate...

National Institutes of Health Job Summary The National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health (NIH), is recruiting for a Senior Investigator to serve as Chief of the Genome Integrity and Structural Biology Laboratory (GISBL) within the Division of Intramural Research. The NIEHS is located in Research Triangle Park (RTP), near to the University of North Carolina, North Carolina State University, North Carolina Central University and Duke University. The NIEHS is a premier research institute where intramural investigators study a wide range of important biologic questions related to effects of the environment on human health. GISBL is composed of seven independent research groups that study fundamental mechanisms of genetic stability and instability, including DNA replication and repair utilizing state-of-the-art structural biology techniques, genetics, biochemistry and cell biology to provide insights into biological...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. About the role: The Mechanistic Cognitive Neuroscience NeuroEngineering Team (MCN-NET) serves as a resource across all MCN labs at Janelia, designing, developing, and deploying groundbreaking engineering tools to further the capabilities of neuroscience...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. About the role: In this role, you will work with other team members and our collaborators in support of various efforts in the development, validation, and application of novel molecular research tools such as molecular sensors, affinity reagents,...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. Intro: Are you interested in playing a role in groundbreaking science? Do you want to contribute to the development of laboratory techniques that help research understand cell structure, cell interactions, and protein localization? Do you have exceptional...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. About the lab and research area: The Liu lab is interested in understanding the cellular and circuitry mechanisms that underlie the communication between the respiratory system and the nervous system. We use mouse as the model organism and combine...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. About the Role: Are you passionate about stem cell research and interested in advancing scientific discoveries? We are seeking a highly motivated and skilled individual to join the Primary & iPS Cell Culture Shared Resource team at Janelia as a...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. About the Department: Janelia's GENIE Project Team (short for Genetically ENcoded Indicators and Effectors) develops and optimizes cutting-edge protein-based fluorescent sensors for imaging various cellular processes. We have collaborated with Janelia...

Howard Hughes Medical Institute Primary Work Address: 19700 Helix Drive, Ashburn, VA, 20147 Current HHMI Employees, click here to apply via your Workday account. The Howard Hughes Medical Institute's Janelia Research Campus is a pioneering research center in Ashburn, Virginia, where scientists pursue fundamental questions in the life sciences. Our integrated teams of biologists, computational scientists, and tool-builders innovate research practices and technologies to solve biology's deepest mysteries. HHMI launched Janelia in 2006, establishing an intellectually enriching environment for scientists to do creative, collaborative, hands-on work. We share our methods, results, and tools with the scientific community. About the role: The Site Supply Technician will provide laboratory and administrative support and services to the entire campus, working in any of the Site Supply and Service departments: Shipping/Receiving, Mailroom, and Glasswash. The Technician will...

Site Name: USA - Pennsylvania - Upper Providence, Cambridge MA, GSK HQ, UK - Hertfordshire - Stevenage, USA - Massachusetts - Waltham, USA - North Carolina - Carolinas, Waltham Posted Date: Aug 21 2024 We have an exciting opportunity at GSK for a highly motivated and experienced Director level Quantitative Systems Pharmacology (QSP) Expert to join our team supporting oncology therapeutic area as part of the global Clinical Pharmacology Modelling and Simulation (CPMS) department. Delivering CPMS excellence to research and development programs using quantitative pharmacology approaches, as part of the model-informed drug discovery & development paradigm (MID3), to get innovative oncology therapies faster to the right patients at the right dose. JOB PURPOSE: As a Director-level Quantitative Systems Pharmacology (QSP) Expert, you will develop, guide and apply QSP models to guide clinical study designs and mechanistic interpretation of study results in support of development...

Site Name: USA - Pennsylvania - Upper Providence, Cambridge MA, GSK HQ, UK - Hertfordshire - Stevenage, USA - Massachusetts - Waltham, USA - North Carolina - Carolinas, Waltham Posted Date: Aug 21 2024 We have an exciting opportunity at GSK for a highly motivated and experienced Director level Quantitative Systems Pharmacology (QSP) Expert to join our team supporting oncology therapeutic area as part of the global Clinical Pharmacology Modelling and Simulation (CPMS) department. Delivering CPMS excellence to research and development programs using quantitative pharmacology approaches, as part of the model-informed drug discovery & development paradigm (MID3), to get innovative oncology therapies faster to the right patients at the right dose. JOB PURPOSE: As a Director-level Quantitative Systems Pharmacology (QSP) Expert, you will develop, guide and apply QSP models to guide clinical study designs and mechanistic interpretation of study results in support of development...