4 associate director computational biology jobs found

Merck Job Description The Precision Genetics group within the Data, AI and Genome Sciences (DAGS)Department is recruitingan Associate Director, Computational BiologyinCardiometabolic DrugDiscoveryData Sciences. We are seeking an experienced computationalbiologist with a proven track-record in applying human genetics to generatetarget/biomarker hypotheses and patient stratification strategies. This role will apply cutting edge AI/MLapproaches to leverage our Company's investments in human genetics and othermultimodal data to support drug discovery in the cardiometabolic disease space. The Associate Director will inform discovery, translational medicine, companion diagnostics and clinicalresearch and partner withdiscovery colleagues in Cardiometabolic Discovery Research to perform analyses to initiatenew projects as well as support ongoing discover projects.This role willimplementrigorous data analysis practices, aligning resources based on scientific priorities, andmentoring...

Merck Job Description The Precision Genetics group within the Data, AI and Genome Sciences (DAGS)Department is recruitingan Associate Director, Computational BiologyinCardiometabolic DrugDiscoveryData Sciences. We are seeking an experienced computationalbiologist with a proven track-record in applying human genetics to generatetarget/biomarker hypotheses and patient stratification strategies. This role will apply cutting edge AI/MLapproaches to leverage our Company's investments in human genetics and othermultimodal data to support drug discovery in the cardiometabolic disease space. The Associate Director will inform discovery, translational medicine, companion diagnostics and clinicalresearch and partner withdiscovery colleagues in Cardiometabolic Discovery Research to perform analyses to initiatenew projects as well as support ongoing discover projects.This role willimplementrigorous data analysis practices, aligning resources based on scientific priorities, andmentoring...

GSK GSK Site Location: Cambridge, MA. On-site presence of 2-3 days per week on average required. Job Purpose: The oligotherapy data science leader role is embedded in and directly supports the Oligo Sciences team whose broad remit is the design, characterization, and early development of oligonucleotide therapies. Oligo data scientists will serve a dual purpose of co-developing a data capture & analysis platform with oligo sciences experts and translating their needs broadly across GSK to build methods/models/capabilities that fulfil them. Key Responsibilities: Co-design and implement a target tractability system for oligo-guided therapeutic mechanisms such as RNA degradation/interference, and up/down modulation of alternative splicing, poly-adenylation, guided RNA editing, etc. Co-develop a target/complex engagement model that combines target sequence, secondary+ tertiary structure, and oligo chemistry to drive binding assay designs for both...

GSK The Oligotherapy Principal Data Scientist role is embedded in and directly supports the Oligo Sciences team whose broad remit is the design, characterization, and early development of oligonucleotide therapies. Oligo data scientists will serve a dual purpose of co-developing a data capture & analysis platform with oligo sciences experts and translating their needs broadly across GSK to build methods/models/capabilities that fulfil them. Key Responsibilities: Co-design and implement a target tractability system for oligo-guided therapeutic mechanisms such as RNA degradation/interference, and up/down modulation of alternative splicing, poly-adenylation, A>I edit, etc. Co-develop a target/complex engagement model that combines target sequence, secondary+ tertiary structure, and oligo chemistry to drive binding assay designs for both high-throughput screening and low-latency optimization. Collaborate effectively with renowned GSK experts in genetics, genomics,...