Jul 11, 2020

Senior Engineer II, Gene Therapy - Technical Development

  • Professional Diversity Network
  • Cambridge, MA, USA

Job Description


Job DescriptionBiogen's Pharmaceutical Operations & Technology (PO&T) Gene Therapy Department is searching for an individual to act as a technical leader for the Cell Culture Development group. The candidate will be expected to collaborate with other groups within the Gene Therapy and Research Departments to drive innovation and characterization of cell culture process technologies to produce AAV viral vectors. Success in this position will require the candidate to enable successful AAV manufacturing through small scale development and provide support for regulatory submissions for early and late phase programs.Responsibilities include:Manage a small team to execute cell culture development studies for early and late phase gene therapy programs. Ensures that the team meets timelines, openly communicates across functions, and maintains a good working environment. Mentor direct reports and guide their career development.Work collaboratively within the Gene Therapy Department and Program Asset management to drive process characterization and relevant documentation to support PPQ or regulatory packages. Support technical transfer teams to ensure successful manufacturing campaigns at CMO facilities as needed.Engagein internal collaborations with other Gene Therapy or Technical Development groups to achieve objectives and implement scientific advancements in the Gene Therapy field.Independently manage technical projects to ensure milestones and timelines are met. Openly communicate across functions and departments while maintaining good collaborative relationships.Provide technical expertise on topics pertaining to cull culture development for both adherent and suspension mammalian cell culture processes. Presents findings and/or results to senior management, external stakeholders, and industry peers at conferences.Scope/Accountability:This individual will manage a group of 2-3 employees responsible for the implementation of cell culture processes for early-stage programs and characterization of late-stage programs. The team is also responsible for scientific and technical innovations to drive development, shorten timelines, and improve production methodologies as the industry evolves.#LI-SK1Qualifications3+ years' experience in cell culture development, bioprocess development and/or related areas.Expertise in process characterization, adherent, and suspension mammalian cell culture techniques, process analytics, cell biology, and bioreactor operations.Experience with AAV biology and viral vector production systems is a plus.Excellent communication skills and a proven track record of publications and presentations.Education: Ph.D. in Bioengineering, Biochemical Engineering, Chemical Engineering, Biochemistry, or related discipline.M.S. degree with relevant industrial experience in Biopharmaceutical development may also be consideredAdditional InformationBiogen's Pharmaceutical Operations & Technology (PO&T) Gene Therapy Department is searching for an individual to act as a technical leader for the Cell Culture Development group.PDN-e799c46a-417a-4e06-929a-117c54440c9a



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