Jun 08, 2024

Staff AI/ML Engineer - Sequence Learning

  • GlaxoSmithKline
  • San Francisco, CA, USA
Full-Time Engineering Science

Job Description

Site Name: USA - California - San Francisco
Posted Date: Jun 6 2024

"Staff AI/ML Engineer - Sequence Learning"

At GSK we see a world in which advanced applications of machine learning and AI will allow us to develop novel therapies to existing diseases and to quickly respond to emerging or changing diseases with personalized drugs, driving better outcomes at reduced cost with fewer side effects. It is an ambitious vision that will require the development of products and solutions at the cutting edge of machine learning and AI. If that excites you, we'd love to chat.

The AI/ML Sequence Learning Team applies machine learning and AI methods to biological sequence (DNA, RNA, protein) data from large-scale human genetic, functional genomic and single cell experiments. Models operating directly on sequence data that can infer how variants alter protein/RNA abundance, structure and function have the potential to be transformative in drug discovery, empowering us to find new life saving medicines.

We are looking for a Staff AI/ML Engineer to help us make this vision a reality. Competitive candidates will have a track record in developing SOTA deep learning models for solving challenging real world scientific problems. You should be an outstanding scientist with in-depth knowledge in modern machine learning. You can convert vaguely described biological/drug discovery challenges into well-defined machine learning problem. You can independently execute and deliver full AI/ML driven solution from sourcing training data, design and implementing SOTA machine learning models, testing, benchmark and product driven research for model performance improvement, to shipping stable, tested, performant code and services in an agile environment.

The AI/ML team is built on the principles of ownership, accountability, continuous development, and collaboration. We hire for the long term, and we're motivated to make this a great place to work. Our leaders will be committed to your career and development from day one.

Basic Qualifications :
  • Graduate studies in Computer Science or Applied Math, undergraduate studies in Computer Science and relevant graduate studies in the life sciences with a focus on AI/ML techniques, or undergraduate studies in Computer Science and equivalent work history. Candidates with graduate studies in CS and biological sciences or equivalent work history will be highly competitive.
  • Highly experienced in developing deep learning models.
  • An outstanding scientist, machine learning engineer, and software engineer. Demonstrate expertise and depth in at least one area and breadth across your expertise.
  • Proficiency with standard deep learning algorithms and model architectures.
  • Familiarity with current deep learning literature and math of machine learning.
  • In depth knowledge in machine learning best practices, scalable training and deployment, model introspection and evaluation.
  • Advanced level in PyTorch, Tensorflow, or other deep learning frameworks.
  • Track record as an independent contributor capable of end-to-end development of ML-powered products for genomics
  • 3+ years experience of professional software development practices: code standards, code review, version control, CI/CD, testing, documentation, Agile, with the ability to mentor others in these practices
  • 2+ years experience in a technical lead position


Preferred Qualifications :
  • PhD in Machine Learning.
  • Knowledge in disease biology, molecular biology and biochemistry.
  • Experience with biological data (e.g., genomics, transcriptomics, epigenomics, proteomics).
  • Peer reviewed publications in major AI conferences.
  • Experience in design, development and deployment of commercial AI/ML software.
  • Track record of contributing to open source projects.
  • Mentality of commit early and often, metrics before models, and shipping high quality production code.
  • Experience with large language models


#LI-GSK
The annual base salary for new hires in this position ranges from $191,250 to $258,750 taking into account a number of factors including work location, the candidate’s skills, experience, education level and the market rate for the role. In addition, this position offers an annual bonus and eligibility to participate in our share based long term incentive program which is dependent on the level of the role. Available benefits include health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and paid caregiver/parental and medical leave.
Please visit GSK US Benefits Summary t o learn more about the comprehensive benefits program GSK offers US employees.

Why GSK?

Uniting science, technology and talent to get ahead of disease together.

GSK is a global biopharma company with a special purpose - to unite science, technology and talent to get ahead of disease together - so we can positively impact the health of billions of people and deliver stronger, more sustainable shareholder returns - as an organisation where people can thrive. We prevent and treat disease with vaccines, specialty and general medicines. We focus on the science of the immune system and the use of new platform and data technologies, investing in four core therapeutic areas (infectious diseases, HIV, respiratory/ immunology and oncology).

Our success absolutely depends on our people. While getting ahead of disease together is about our ambition for patients and shareholders, it’s also about making GSK a place where people can thrive. We want GSK to be a place where people feel inspired, encouraged and challenged to be the best they can be. A place where they can be themselves - feeling welcome, valued, and included. Where they can keep growing and look after their wellbeing. So, if you share our ambition, join us at this exciting moment in our journey to get Ahead Together.

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